Skin Rejuvenation
Polynucleotides
A next-generation biostimulator that harnesses your skin's own regenerative biology — improving texture, hydration, firmness and radiance from within.
About the Treatment
What Are Polynucleotides?
Polynucleotides (PNs) — also known as PDRN (polydeoxyribonucleotide) — are long chains of nucleotides derived from highly purified salmon or trout DNA. When injected into the skin, they act as a powerful biostimulator, activating the skin's own repair mechanisms to produce collagen, improve hydration, and regenerate damaged tissue.
Unlike dermal fillers, which add volume, or skin boosters, which primarily hydrate, polynucleotides work at a cellular level — stimulating fibroblast activity and encouraging genuine tissue remodelling. The result is a progressive, natural improvement in skin quality, firmness, and radiance that builds over time.
Polynucleotides are suitable for a wide range of skin concerns and are increasingly recognised as one of the most effective treatments available for improving overall skin health. They are biocompatible, biodegradable, and have an excellent safety profile — making them a popular choice for clients seeking meaningful, long-lasting results without dramatic intervention.
The Process
How It Works
Consultation
We begin with a thorough consultation to assess your skin concerns, medical history, and suitability for treatment. This allows us to design a personalised plan tailored to your goals.
Preparation
The treatment area is cleansed and, where appropriate, a topical numbing cream may be applied to maximise your comfort during the procedure.
Injection
The polynucleotide solution is carefully injected into the skin using fine needles. The technique and depth of injection are tailored to the area being treated and the results you are looking to achieve.
Aftercare
Following treatment, you may experience mild redness, swelling, or bruising — this is normal and typically resolves within a few days. We will provide full aftercare guidance to support your recovery and results.
Course of Treatments
For optimal results, a course of 3–4 sessions spaced 2–4 weeks apart is typically recommended. Maintenance treatments every 6–12 months can help sustain the benefits long term.
Skin Concerns
What Polynucleotides Can Treat
Fine Lines & Wrinkles
Stimulates collagen to smooth fine lines and improve overall skin texture over time.
Skin Laxity
Improves firmness and elasticity in areas where the skin has begun to lose its structure.
Dull or Tired-Looking Skin
Revives radiance and improves overall skin tone for a healthier, more refreshed appearance.
Dehydrated Skin
Supports the skin's natural moisture-retaining capacity for a plumper, more hydrated complexion.
Acne Scarring
Encourages tissue remodelling to reduce the appearance of acne scars and uneven texture.
Dark Circles & Under-Eye Hollows
A popular treatment for the delicate under-eye area to reduce hollowness and improve skin quality.
Sun Damage & Pigmentation
Helps to even out skin tone and reduce the visible effects of sun damage and environmental ageing.
Hair Loss (Scalp)
Polynucleotides can be used on the scalp to support hair follicle health and encourage regrowth.
Our Philosophy
Our Approach
Clinically Evidenced
Polynucleotides are backed by a growing body of clinical research. We use only high-quality, pharmaceutical-grade products from trusted suppliers.
Tailored to You
Every treatment plan is personalised. We assess your skin, discuss your goals, and recommend the right protocol — never a one-size-fits-all approach.
Natural-Looking Results
Polynucleotides work with your skin's own biology, producing gradual, natural improvements rather than dramatic or artificial-looking changes.
Honest Guidance
We will always give you a realistic picture of what to expect, including how many sessions are likely to be needed and what results are achievable for your skin type.
Investment
Pricing
A course of 3–4 sessions is recommended for optimal results. Prices below are indicative — a full quote will be provided at your consultation.
Prices are indicative and may vary depending on the product used and the extent of treatment required. A consultation is required before treatment.
Common Questions
Frequently Asked Questions
Quick Links
Ready to Get Started?
Book Your Polynucleotide Consultation
All treatments begin with a thorough consultation to assess your skin and design a personalised plan. We look forward to welcoming you to the clinic.